週次 |
日期 |
單元主題 |
第1週 |
09/16 |
Introduction |
第2週 |
09/23 |
Structural and Chemical Properties of Biological Macromolecules |
第3週 |
09/30 |
Protein Crystallography |
第4週 |
10/07 |
Principle of Nuclear Magnetic Resonance Spectroscopy |
第5週 |
10/14 |
Biomolecular NMR technique |
第6週 |
10/21 |
Multi-dimesional NMR for protein determination |
第7週 |
10/28 |
Biophysical Methods to Probe Non-covalent Molecular Interaction (I):Circular Dichroism, UV and Fluorescence Spectroscopy |
第8週 |
11/04 |
Biophysical Methods to Probe Non-covalent Molecular Interaction (II):Surface Plasmon Resonance and ITC |
第9週 |
11/11 |
Mid-term |
第10週 |
11/18 |
Structural Basis of Signal Transduction and Post-translation Modification |
第11週 |
11/25 |
Molecular Enzymology |
第12週 |
12/02 |
Protein/peptide interaction with membrane |
第13週 |
12/09 |
Structural Features of Receptors and ligands |
第14週 |
12/16 |
Structural View of Protein-DNA Recognition in Gene Regulation |
第15週 |
12/23 |
Analytical Ultracentrifugation |
第16週 |
12/30 |
Molecular Docking and Bioinformatics Approach |
第17週 |
01/06 |
Strategies for Drug Discovery, Rational Drug Design versus Drug screen |
第18週 |
01/13 |
final-exam |